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Semax + Selank + BPC-157 + KPV - Bodhi
Also indexed as The trade title "Bodhi", Selank across three, KPV across free acid and C-terminal amide
1 Identity
Fixed-ratio four-component article: two unmodified all-L heptapeptide free acids, a 15-residue all-L gastric-juice-derived pentadecapeptide free acid, and an all-L tripeptide free acid corresponding to the alpha-MSH(11-13) segment. No metal center, no acyl chain, no conjugate, no disulfide, no non-proteinogenic residue. and three of the four components carry an unresolved terminal fork in the market — Semax across four forms.
Contains Semax + Selank + BPC-157 + KPV
- Sequence
- Per component, cross-referenced to each component's own record. Semax H-Met-Glu-His-Phe-Pro-Gly-Pro-OH. Selank H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH. BPC-157 H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH (GEPPPGKPADDAGLV). KPV H-Lys-Pro-Val-OH, the free acid. The KPV C-terminal amide and the KdPT sequence Lys-D-Pro-Thr are different articles, not synonyms.
- Molecular formula
- Per component; a mixture has no combined formula and none is written. Semax C37H51N9O10S; Selank C33H57N11O9; BPC-157 C62H98N16O22; KPV C16H30N4O4 as the free acid. Semax is the only sulfur-bearing chain, and the isotope envelope assigns it without reference to retention. Counterion is measured per component, and the risk is concrete on this article: acetate on some components against trifluoroacetate at high mass fraction on others passes a gross-weight check while the ratio is already out.
- Average mass
- Per component, on IUPAC 2021 abridged conventional atomic weights: Semax 813.928 Da; Selank 751.887 Da; BPC-157 1419.56 Da; KPV 342.44 Da. AT A nominal 10 mg each, 40 mg total, the 1 : 1 : 1 : 1 mass ratio is a molar ratio of 1.744 : 1.888 : 1.000 : 4.145 against BPC-157 — 12.28610, 13.29987, 7.04444 and 29.20220 micromol. A 342 Da tripeptide against a 1,420 Da pentadecapeptide at equal mass is four times the molar quantity, and that is the widest molar spread among the equal-mass neuro blends in this catalog.
- Monoisotopic mass
- Per component. Semax 813.34796, [M+H]+ 814.35524. Selank 751.43407, [M+H]+ 752.44135. BPC-157 1418.7042, [M+H]+ 1419.7115, [M+2H]2+ 710.3594. KPV 342.22671, [M+H]+ 343.23399. Note the coincidence a careless method will meet: BPC-157 doubly charged at m/z 710.36 sits 42 Th below Selank singly charged at 752.44 and inside the same scan window, so charge-state assignment must be shown rather than assumed. KPV at 342 requires acquisition below 343 m/z.
- Salt / variant note
- (1) the semax fork: 813.928, 812.94, 855.965, 854.981. (2) the Selank fork: 751.887, 750.90, 793.924, 792.940. (3) the KPV fork: free acid 342.44 against C-terminal amide 341.46, both shipped under the title "alpha-MSH(11-13)" by different institutional suppliers, and KdPT (Lys-D-Pro-Thr) at 344.41, a different sequence with a D-proline. (4) BPC-157: acetate and arginate salt forms are carried as separate catalog records and are not interchangeable on a certificate. (5) ratio: no standard was located, and products of this description circulate at ratios that no located source fixes.
2 Class & testing panel
- Form
- Fixed-ratio blend
- Testing panel
- P1 — panel definitionfor all four components, run per component and never once for the vial; the union adds nothing beyond P1. The governing analytical fact here is not panel breadth but detection: semax is the only component with an aromatic residue. Selank, BPC-157 and KPV contain no tryptophan, tyrosine or phenylalanine, so three of the four components are invisible above roughly 220 nm and quantitation must be at 214 nm with per-component response factors, or by mass spectrometry; one aromatic-bearing component out of four also makes any single-wavelength ultraviolet result on this article a partial result. The second method fact is KPV: each of its three residues — lysine, proline and valine — is also present in BPC-157, so KPV carries no unique marker residue in this vial and its net content is determined by its own LC-MS/MS method rather than by the marker-residue deconvolution that serves it in the copper blends
3 Primary sources & evidence
Published literature exists for each component, is graded on that component's record and is cross-referenced rather than restated. The BPC-157 file is the largest of the four. The KPV file is entirely preclinical and analytical, and the human ulcerative-colitis material that circulates under the KPV name belongs to KdPT, a different molecule. None of that literature is literature about this mixture: no published study of this fixed four-component combination, and no consensus specification for it, was located.
4 Storage & specification
- Storage
- White to off-white co-lyophilized cake in Type I amber glass with a PTFE-lined closure, nitrogen headspace and in-pack desiccant; a non-sterile laboratory chemical, with no sterility claim and no injection format. Store at -20 degrees C plus or minus 5 degrees C, desiccated and protected from light, the oxygen and light controls being set by the Semax Met1 thioether. Vials are equilibrated to ambient before opening, which matters more here than on the two-component articles because a 342 Da tripeptide takes a large proportional insult from condensed moisture and its diketopiperazine route is moisture- and temperature-accelerated.
- Shelf life
- Provisional 24 months at -20 degrees C plus or minus 5 degrees C, desiccated and light-protected, from QA release — the shortest of the four component intervals, provisional pending this company's own data. Stability-indicating attributes are per-component net content with KPV by its own LC-MS/MS method, all three pairwise ratios, methionine sulfoxide, cyclo(Lys-Pro) and free valine, BPC-157 aspartate-related degradants, water, counterion and any new peak above 0.10 percent.
This record reports identity, specification and study design. It does not state what the article does in a human body. Supplied under the caution: “CAUTION: Contains a new drug for investigational use only in laboratory research animals or for tests in vitro. Not for use in humans.”
