SLU-PP-332 + BAM15 - oral research blend

1 Identity

Fixed-ratio two-component article, and no peptide bond exists anywhere in the vial. One N-acylhydrazone, (E)-4-hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide, and one fused heterocycle, N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine. Both achiral, both neutral crystalline solids rather than salts, neither lyophilized. Each component's full identity lives on its own record in the catalog and is cross-referenced from here rather than restated. Neither component is A peptide, and the title's presence in a peptide catalog is a category error with practical consequences: peptide handling, storage and stability assumptions do not transfer to either molecule, and neither does a peptide release panel.

Sequence

None, and none can exist for either component. There are no amino acids and no peptide bond in this vial. The identifiers that replace a sequence are the full structural names given above and a certified reference standard for each: identity on both components rests on NMR against that standard and on retention-time co-elution, with mass as a confirmatory rather than a primary test.

Molecular formula

Per component; a mixture has no combined formula and none is written. SLU-PP-332 C18H14N2O2 — no sulfur, no halogen, no metal. BAM15 C16H10F2N6O. The two fluorines and six nitrogens of BAM15 give it a distinctive isotope pattern, and its M+1 relative intensity is itself an identity check that SLU-PP-332 cannot mimic. Neither is supplied as a salt, so there is no counterion arithmetic on either side and gross weight is the article.

Average mass

Per component, on IUPAC 2021 abridged conventional atomic weights: SLU-PP-332 290.322 Da; BAM15 340.294 Da. AT A nominal 10 mg plus 10 mg fill, 20 mg total, that is 34.4445 and 29.3864 micromol — a molar ratio of 1.1721 : 1.0000. Because neither component is a salt or a hydrate, the mass ratio and the weighed ratio are the same quantity here, which is not so wherever a counterion or water of hydration intervenes. No single blend molecular weight is printed.

Monoisotopic mass

Per component. SLU-PP-332 290.10553 neutral, [M+H]+ 291.11280, [M-H]- 289.09825, [M+Na]+ 313.09475. BAM15 340.0884 neutral, [M+H]+ 341.0957, [M-H]- 339.0811. The two are 49.97 Da apart and trivially resolved from each other. Mass is A weak identity test on the first component and the record says so: the E and Z geometric isomers of the C=N bond and the naphthalen-1-yl regioisomer are all isobaric to the last decimal, so NMR against a certified standard carries that identity and mass confirms it.

Salt / variant note

Neither component is supplied as a salt, so the forks here are isomers, degradants and purity grades rather than counterions. (1) ratio: none is standard and none is captured with a source. (2) SLU-PP-332 geometric isomers: the E and Z forms of the C=N bond, isobaric, separated only chromatographically or by NMR; the naphthalen-1-yl regioisomer is likewise isobaric. (3) hydrolysis products of the same component: 4-hydroxybenzohydrazide and 2-naphthaldehyde, the reverse of the condensation that forms it, both named impurities rather than unknowns. (4) BAM15 purity grades observed from 95.00 percent to greater than 98 percent across suppliers, which is a specification difference and not a naming one.

2 Class & testing panel

Form

Fixed-ratio blend

Testing panel

P6 — panel definitionfor both components, run per component and never once for the vial. The panel exclusions are as important as its contents and are stated on the certificate as disclosures rather than left blank: no sequence, no net peptide content, no amino acid analysis, no counterion in the peptide sense, no chiral method — neither molecule has a stereocenter — and no peptide-panel endotoxin line. A document offering any of those for this article has run a peptide template against two small molecules and was not read by whoever signed it. The peptide vocabulary is translated rather than applied verbatim: net peptide content becomes a w/w assay, and a unique marker residue becomes an independent chromophore. QNMR is available on both components and is used

3 Primary sources & evidence

The index reports the design and provenance of the literature, not a conclusion about effect.

Published literature exists for each component, is graded on that component's record and is cross-referenced from here rather than restated; both are established laboratory tool compounds carried by reference-standard houses with published purity specifications, which is the ordinary research-chemical channel. None of that literature is about this fixed two-component mixture: no published study of the combination at any ratio has been identified, and no published specification for one was found. That is a statement about the search rather than a finding about the combination, and what governs acceptance of a blend lot is the per-component evidence read alongside the measured ratio.

4 Storage & specification

Storage

Two neutral crystalline solids co-blended rather than co-lyophilized, in Type I amber glass with a PTFE-lined closure and in-pack desiccant; a non-sterile laboratory chemical with no sterility claim. Store at -20 degrees C plus or minus 5 degrees C, tightly closed, desiccated and protected from light. The light and moisture conditions are set by the acylhydrazone, whose principal chemical liability is hydrolysis of the C=N bond back to its two starting materials, and the label states that reason rather than leaving the condition unexplained.

Shelf life

Provisional at 24 months at -20 degrees C plus or minus 5 degrees C from QA release, provisional pending the company's own data; the blend runs its own protocol and inherits neither component study. Stability-indicating attributes: per-component assay, the measured ratio, the two acylhydrazone hydrolysis products, E-to-Z isomerization, water, residual solvents and any new peak above 0.10 percent. Pulls at 0, 3, 6, 12, 18, 24 and 36 months, with a 6-month interim pull on each of the first three lots. A physical-blend uniformity study on the first three lots is required before Weight Variation could replace full content uniformity.