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Lipopeptide (Palmitoyl Hexapeptide-12 / Biopeptide EL)
Also indexed as INCI Palmitoyl Hexapeptide-12, legacy INCI Palmitoyl Oligopeptide, the trade name Biopeptide EL, Pal-VGVAPG
1 Identity
Defined single synthetic lipopeptide, an elastin hydrophobic-domain hexapeptide N-palmitoylated on the Val1 alpha-amino group. But see status: the trade product is not the molecule. and "elastin peptide". Sold as "Lipopeptide 10mg" by one seller and as "Lipopeptide (Biopeptide EL) (200mg)" by two others.
- Sequence
- Palmitoyl-Val-Gly-Val-Ala-Pro-Gly-OH (Pal-VGVAPG). Palmitoylation on the N-terminal alpha-amino group; free acid C-terminus.
- Molecular formula
- C38H68N6O8
- Average mass
- 736.996 Da.
- Monoisotopic mass
- 736.50986 Da monoisotopic neutral; [M+H]+ 737.51714.
- Salt / variant note
- Pal-GHK, that is Palmitoyl Tripeptide-1, sold as Biopeptide CL and already a separate record in this catalog, is the collision. Pal-KTTKS, sold as Matrixyl and in this catalog. Pal-GQPR. Palmitoyl Tetrapeptide-7, in this catalog. Palmitoyl Tripeptide-38, in this catalog. And the antibiotic and antifungal lipopeptides, which share the class name and nothing else.
2 Class & testing panel
- Form
- Single article
- Testing panel
- P1 — panel definition
3 Primary sources & evidence
Identity is settled and the formula is concordant across three independent sellers. The cosmetic efficacy literature is not reproduced and is not adopted.
4 Storage & specification
- Storage
- Lyophilized or as supplied, -20 degrees C plus or minus 5 degrees C, desiccated, protected from light. The palmitoyl chain makes the article prone to poor aqueous solubility and to adsorption onto container surfaces.
- Shelf life
- Provisional 24 months at -20 degrees C, assigned by protocol.
This record reports identity, specification and study design. It does not state what the article does in a human body. Supplied under the caution: “CAUTION: Contains a new drug for investigational use only in laboratory research animals or for tests in vitro. Not for use in humans.”
