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Humanin HNG (S14G-Humanin)
Also indexed as S14G-Humanin, HNG and [Gly14]-Humanin
1 Identity
Linear synthetic 24-residue peptide, an analog of humanin carrying a serine-to-glycine substitution at position 14. One seller lists it as 'humanin HNG peptide 5MG vial'.
- Sequence
- 24 residues; the humanin sequence with Ser14 replaced by Gly. The substitution is the only difference from the parent and it is a 30 Da deletion of the serine side chain.
- Molecular formula
- C118H202N34O31S2
- Average mass
- 2657.241 Da average, arithmetic from the stated formula rather than measured.
- Monoisotopic mass
- 2655.47167 Da monoisotopic neutral; [M+H]+ 2656.47895.
- Salt / variant note
- Humanin itself, already in this catalog — the wild type differs from this article by the Ser14 side chain, and the two are separated by roughly 30 Da on a 2,657 Da peptide, which is resolvable on a good instrument and completely lost on a poor one. Also the various humanin-family peptides and the small humanin-like peptides. Also colliding by class: MOTS-c and its variants, already held here.
2 Class & testing panel
- Form
- Single article
- Testing panel
- P1 — panel definition
3 Primary sources & evidence
Identity evidence is moderate — two institutional catalog listings with a concordant formula, with the masses arithmetic from that formula rather than measured. No physiological claim is made or adopted.
4 Storage & specification
- Storage
- Lyophilized powder, stored at -20 degrees C plus or minus 5 degrees C, desiccated and protected from light. Not to be stored in solution, given the methionine content.
- Shelf life
- Provisional 24 months at -20 degrees C, assigned by protocol and not measured.
This record reports identity, specification and study design. It does not state what the article does in a human body. Supplied under the caution: “CAUTION: Contains a new drug for investigational use only in laboratory research animals or for tests in vitro. Not for use in humans.”
