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Humanin HNG (S14G-Humanin)

Also indexed as S14G-Humanin, HNG and [Gly14]-Humanin

1 Identity

Linear synthetic 24-residue peptide, an analog of humanin carrying a serine-to-glycine substitution at position 14. One seller lists it as 'humanin HNG peptide 5MG vial'.

Sequence
24 residues; the humanin sequence with Ser14 replaced by Gly. The substitution is the only difference from the parent and it is a 30 Da deletion of the serine side chain.
Molecular formula
C118H202N34O31S2
Average mass
2657.241 Da average, arithmetic from the stated formula rather than measured.
Monoisotopic mass
2655.47167 Da monoisotopic neutral; [M+H]+ 2656.47895.
Salt / variant note
Humanin itself, already in this catalog — the wild type differs from this article by the Ser14 side chain, and the two are separated by roughly 30 Da on a 2,657 Da peptide, which is resolvable on a good instrument and completely lost on a poor one. Also the various humanin-family peptides and the small humanin-like peptides. Also colliding by class: MOTS-c and its variants, already held here.

2 Class & testing panel

Form
Single article
Testing panel
P1panel definition

3 Primary sources & evidence

The index reports the design and provenance of the literature, not a conclusion about effect.

Identity evidence is moderate — two institutional catalog listings with a concordant formula, with the masses arithmetic from that formula rather than measured. No physiological claim is made or adopted.

4 Storage & specification

Storage
Lyophilized powder, stored at -20 degrees C plus or minus 5 degrees C, desiccated and protected from light. Not to be stored in solution, given the methionine content.
Shelf life
Provisional 24 months at -20 degrees C, assigned by protocol and not measured.

This record reports identity, specification and study design. It does not state what the article does in a human body. Supplied under the caution: “CAUTION: Contains a new drug for investigational use only in laboratory research animals or for tests in vitro. Not for use in humans.