HGH 191AA / Somatropin

1 Identity

Recombinant protein, 191 amino acids, non-glycosylated, two disulfide bridges at Cys53-Cys165 and Cys182-Cys189. Sequence-identical to pituitary-derived 22 kDa human growth hormone. Brands: Genotropin, Humatrope, Norditropin, Nutropin.

Sequence

Recombinant protein; the sequence is not reproduced here. 191 residues.

Molecular formula

C990H1528N262O300S7 as the free-base backbone.

Average mass

22,125 Da, stated verbatim in the FDA labels for Omnitrope and Nutropin.

Monoisotopic mass

Not available. There is no authoritative published monoisotopic value; at 22 kDa the isotope envelope is resolvable only on high-end instruments and no reference figure exists.

Salt / variant note

Somatrem, 192 residues with an N-terminal methionine — discontinued, and named explicitly in 333(e)(4). The 20 kDa hGH isoform, 176 residues, which is the basis of the WADA isoform-ratio test. HGH Fragment 176-191 and AOD-9604, both already recorded in this catalog and both routinely cross-filed under 'HGH' by sellers. Somatrogon, lonapegsomatropin and somapacitan, which are separate licensed biologics and not somatropin. And the entire growth-hormone-secretagogue block of this catalog — CJC-1295, ipamorelin, tesamorelin, sermorelin, hexarelin, MK-677 — which sellers file adjacent to it and buyers conflate with it.

2 Class & testing panel

Form

Single article

Testing panel

Special-class panel — panel definition

3 Primary sources & evidence

The index reports the design and provenance of the literature, not a conclusion about effect.

Regulatory and statutory evidence is complete, authoritative and quotable. Nine separate NDAs appear on FDA's published transition list with their approval dates. The statutory text above is reproduced from the United States Code.

4 Storage & specification

Storage

Not assigned. The article is not offered.

Shelf life

Not assigned. The article is not offered.