DMAA (1,3-dimethylamylamine)

1 Identity

Non-peptide small molecule — branched aliphatic primary amine. Contains no amide bond and has no structural relationship to any other article in this catalog.

Sequence

No sequence and no peptide bond of any kind. The article is 4-methylhexan-2-amine: a branched aliphatic primary amine, volatile and strongly basic. Two stereocenters, at C2 and C4, give four stereoisomers in two diastereomeric pairs — (2R,4S)/(2S,4R) and (2R,4R)/(2S,4S). Synthetic material is a mixture of all four in a ratio that varies with synthetic route and is not fixed by the chemical name, so a bare purity figure from an achiral method is not an identity for this substance. Whether the compound occurs at all in Pelargonium graveolens is contested in the analytical literature, with the majority of independent analyses reporting non-detection; the company does not rely on a botanical origin for any purpose and does not repeat the claim.

Molecular formula

C7H17N (free base); C7H18ClN, equivalently C7H17N.HCl (hydrochloride). The hydrochloride is the form that is handled, because the free base is a low-boiling volatile amine.

Average mass

115.220 Da free base (C7H17N) and 151.678 Da as the hydrochloride (C7H18ClN), both on IUPAC 2021 conventional atomic weights. Two independent sellers print 151.7 and 151.68 for the same salt, and all three figures agree to the last printed digit. The 36.458 Da gap between the two forms is 24 percent of the salt's weight, so a lot weighed as the hydrochloride and specified against the free base is 24 percent short of the stated substance, and the two published CAS numbers make that substitution look like a clerical matter rather than a different article.

Monoisotopic mass

115.13610 Da free base; 151.11278 Da as the hydrochloride. Working ion for the free base [M+H]+ m/z 116.14338; the hydrochloride is observed as the same protonated cation, so mass spectrometry cannot establish the salt form here, and the salt form must be established by chloride determination or by elemental analysis, which is a specification requirement and not a preference. A plus or minus 5 ppm window on the free-base neutral is plus or minus 0.0006 Da.

Salt / variant note

A whole family of near-neighbor amines was introduced into this supply channel precisely because they are not DMAA, and every one is separable by arithmetic. (1) free base against hydrochloride — 115.220 against 151.678, a 36.458 Da difference and completely different physical behavior; two CAS numbers, 105-41-9 and 13803-74-2, used interchangeably across listings. (2) 1,4-DMAA, 2-amino-5-methylheptane, C8H19N, 129.247 avg / 129.15175 mono free base; hydrochloride C8H20ClN, 165.705 / 165.12843. One CH2 heavier, 14.027 Da. (3) OCTODRINE / DMHA, 2-amino-6-methylheptane, C8H19N — the same 129.247 average and 129.15175 monoisotopic as 1,4-DMAA. A positional isomer: identical formula, identical mass, distinguishable only by chromatographic retention against an authentic standard or by fragmentation pattern, and accurate mass cannot solve it. (4) 1,3-DMBA / AMP citrate, 4-methylpentan-2-amine, C6H15N, 101.193 avg / 101.12045 mono; hydrochloride C6H16ClN, 137.651 / 137.09713. One CH2 lighter. An analytical technical paper from a reagent house documents all four as compounds found in sports and weight-loss supplements, which is the clearest available statement that substitution within this set is the normal case rather than the exception. (5) stereochemistry as the provenance variant: two stereocenters, four stereoisomers, two diastereomeric pairs; one seller ships and declares a mixture of diastereomers, which is what synthetic material is, and the diastereomer ratio is the only measurement that speaks to synthetic route.

2 Class & testing panel

Form

Single article

Testing panel

P6 — panel definition

3 Primary sources & evidence

The index reports the design and provenance of the literature, not a conclusion about effect.

Analytical literature, by document type. The SWGDRUG analytical monograph for DMAA — a method and reference-data document. An analytical technical paper from a reagent house documenting octodrine, 1,4-DMAA, 1,3-DMAA and 1,3-DMBA as compounds found in sports and weight-loss supplements — an analytical survey. A contested botanical-occurrence literature, with the majority of independent analyses reporting non-detection in Pelargonium graveolens — analytical chemistry, not pharmacology. No statement is made here about what the compound does in any body, and the pharmacological literature is not summarized in this catalog.

4 Storage & specification

Storage

As the hydrochloride salt: tightly closed container with desiccant, 15 to 25 degrees C, protected from moisture, hygroscopic. The free base is a low-boiling volatile amine that absorbs atmospheric carbon dioxide to form carbamate and would require 2 to 8 degrees C under inert headspace in a septum-sealed vial; the free base is not accepted against this specification.

Shelf life

36 months at 15 to 25 degrees C for the hydrochloride salt, with water content and diastereomer ratio as the tracked attributes on a 0/6/12/24/36-month protocol. The diastereomer ratio is tracked because it is the attribute that identifies synthetic route, and it does not appear in a purity chromatogram.